SEMAX (sometimes mistakenly called “c max”) is a Russian nootropic drug that is used in the form of nasal spray and nasal drops to improve cognitive functions and to treat various medical conditions. The drug belongs to the class of regulatory peptides and is said to have a nootropic, psychostimulatory, neuroprotective, antioxidant and antihypoxic effect. It is known to help increase mental and physical performance.

Semax is a stress-protector One of the most important additional properties of Semax is its stress-protective activity. The drug helps the body to cope with stress of any nature. Semax suppresses the development of distress damage to target tissues – nervous, cardiovascular, and immune, preventing the development of adverse morphological and biochemical changes in them. Adaptogenic action of Semax in unfavorable conditions Clinical studies have shown that Semax maintains the physical and mental performance of a person in uncomfortable external conditions, for example, when the ambient temperature drops or in a rarefied atmosphere high in the mountains. This effect is stipulated by the equalization of the fluctuations in the work of the mediator systems of the brain and the suppression of lipid peroxidation (LPO). When using Semax in both unhealthy and healthy people, the work of nerve centers and nerve pathways is optimized, energy metabolism in nerve cells improves, and cognitive functions are enhanced. At the same time, Semax does not have any negative effect on the cardiovascular system.

Semax nootropic does not interact with most medications, given its chemical structure (heptapeptide is a synthetic analogue of adrenocorticotropic hormone, completely devoid of hormonal activity), the rate of absorption and the rate of entry into the blood, as well as the intranasal route of administration.

Semax has a long history of practical use, since the 1990s. The drug has undergone preclinical and clinical trials; its efficacy and safety have been confirmed by a large number of scientific publications. Semax is stated to be one of the safest medications in Russia and worldwide. Over more than 17 years of its case history no major side effects or symptoms of overdose have been recorded except from rare cases of mild irritation of the nasal mucosa. Semax studies have shown that: The drug does NOT cause withdrawal syndrome; It does not negatively affect the nervous, cardiovascular and respiratory systems; The drug doesn’t have an impact on the emotional state in healthy people; neither does Semax cause an increased feeling of depression or anxiety.

Semax does not interact with alcohol, so the concurrent use of the two is acceptable. When taking Semax, alcohol intoxication occurs later and with higher doses of alcohol, and Semax also reduces the morning symptoms of alcohol intoxication.

During clinical trials Semax was given to children as young as several months old to treat perinatal brain injuries and it demonstrated safety and efficacy. Semax 0.1% has a good practical history of treating ADHD. Due to its properties it helps to inhibit manifestations of ADHD, encouraging better child’s adjustment at school. Semax is known to increase diligence, it has a positive impact on the retention of new information and it decreases emotional instability of a child.